Scholar Project Database

Characterizing Hemodynamics of Soft Prosthetic Venous Valves for Caval Valve Implantation

Medical School/Institution:
Project Location/Site: Massachusetts Institute of Technology
Key Outcomes:
1. Leaflet geometries vary stress and Endothelial Cell Activation Potential (ECAP) for the same flow waveform 2. Soft leaflet closure in silico shows vortices may reduce thrombogenicity 3. Coaptation length changes with GOA, Diameter:Height ratio and Height alone 4. Computational simulations and fully coupled Fluid Structure Interaction predicts closing geometry 5. Open and closed geometries of soft bileaflet and soft trileaflet